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Publications

Peer-reviewed papers, conference abstracts, book chapters and patents in which AVABIO products were used. Twenty-seven entries, spanning 1996 to 2025, across rodent, rabbit, canine, swine and non-human primate models.

Reprints of published papers in which AVABIO devices were used

Recent

Pharmacokinetic modeling and efficacy of ceftobiprole medocaril against pneumonic tularemia in cynomolgus macaques

Hahn et al., Antimicrobial Agents and Chemotherapy, 2025.doi:10.1128/aac.01278-25
Cath-In-Cath portsinfusion setsprimate

Comparison of antisense oligonucleotide distribution following intracerebroventricular and lumbar intrathecal routes of administration

Boyd et al., Molecular Therapy - Nucleic Acids 36(4) 102742, 2025.doi:10.1016/j.omtn.2025.102742
Intrathecal and intracerebroventricular accesscathetercanine

Efficacy of intravenously administered gepotidacin in cynomolgus macaques following a Francisella tularensis inhalational challenge

Jakielaszek et al., Antimicrobial Agents and Chemotherapy 67(5) e01381-22, 2023.doi:10.1128/aac.01381-22
Dual Cath-In-Cath ports24 animalsprimate

Intensive care unit-like care of nonhuman primates with Ebola virus disease

Blair et al., The Journal of Infectious Diseases 224(4) 632-642, 2021.doi:10.1093/infdis/jiaa781
Cath-In-Cath systemfemoral venous accessUSAMRIIDprimate

Parenteral nutrition formulation

US Patent Application US20220160669A1, 2022.
6000 CMS multi-therapy infusion pumpcontinuous infusion

Automated blood sampling in canine telemetry studies: enabling enhanced assessments of cardiovascular liabilities and safety margins

Koshman et al., Journal of Pharmacological and Toxicological Methods, 107109, 2021.doi:10.1016/j.vascn.2021.107109
Vascular access portcanineblood sampling

Automated blood sampling in canine telemetry model: enhanced assessment of immune liabilities

Koshman et al., Journal of Pharmacological and Toxicological Methods 112, 107115, 2021.doi:10.1016/j.vascn.2021.107115
Tapered rounded-tip catheterAbbViecanine

Automated blood sampling in a canine telemetry cardiovascular model

Wilsey et al., Comparative Medicine 71(2) 133-140, 2021.doi:10.30802/AALAS-CM-20-000083
Vascular access portcathetercanine

The fluorocycline TP-271 is efficacious in models of aerosolized Francisella tularensis SCHU S4 infection in BALB/c mice and cynomolgus macaques

Grossman et al., Antimicrobial Agents and Chemotherapy 61(8) e00448-17, 2017.doi:10.1128/AAC.00448-17
Cath-In-Cath portsinfusion setsmouse, primate

The fluorocycline TP-271 is efficacious in models of aerosolized Bacillus anthracis infection in BALB/c mice and cynomolgus macaques

Grossman et al., Antimicrobial Agents and Chemotherapy 61(10) e01103-17, 2017.doi:10.1128/AAC.01103-17
Dual Cath-In-Cath 2 ALAT-6 portsBattellemouse, primate

Reference texts

Non-Clinical Vascular Infusion Technology, Volume 2: The Techniques

Green and Healing, CRC Press, 2013, pp. 135-137, 172, 193-198, 265.
Cath-In-Cath portsinfusion setsPCA 50 and 6000 pumpsprimate, dog, swine, juvenile

A Comprehensive Guide to Toxicology in Preclinical Drug Development

Faqi, Academic Press, 2013, pp. 277-306.
Cath-In-Cath portsinfusion setspumpsFastTether 2

Conference and applied work

Eravacycline is efficacious in a Francisella tularensis-infected cynomolgus monkey model

Sutcliffe et al., Tetraphase Pharmaceuticals, CUBRC, Battelle Biomedical Research Center, ASM Biodefense poster, 2014.
Cath-In-Cath portsinfusion setsprimate

An improved system for surgically implanted in-dwelling catheterization for long-term intravenous infusion in cynomolgus monkeys, using 2% taurolidine-citrate to maintain catheter patency

Tavcar, Society of Toxicology, poster 1913, LAB Research, Laval QC, 2011.
Cath-In-Cath portsinfusion setspatencyprimate

Refining a CSF collection model in cynomolgus macaques (M. fascicularis) for biomarker studies

Medina et al., AALAS, Abbott Laboratories, Department of Comparative Medicine, 2011.
Cath-In-Cath portsCSFCathinfusion setsprimate

Age and associated growth correlated with complications of the femoral catheter component of a vascular access port system in juvenile cynomolgus monkeys

Rose, Pickel and Resendez, AALAS, MPI Research, 2011.
Cath-In-Cath portsinfusion setsjuvenile primate

A postpartum developmental study of Göttingen minipigs over three defined pediatric stages

Beck et al., Academy of Surgical Research, Wil Research, 2009.
Cath-In-Cath portsinfusion setsswine

Infusion technology: past, present and future

Crowe, Animal Lab News, November/December 2008.
Cath-In-Cath ports6000 CMS pumpPCA 50 pumps

Ambulatory continuous intravenous infusion model for pregnant Dutch Belted rabbits

Gleason et al., AALAS, Wil Research, 2008.
Cath-In-Cath portsinfusion setsCrono PCA 50 ambulatory syringe pumpjacketsrabbit

Development of an ambulatory continuous infusion method in the non-human primate

Lambert et al., AALAS, Wil Research, 2008.
Cath-In-Cath portsinfusion setsCrono PCA 50 ambulatory syringe pumpjacketsprimate

Evaluation of a new quick-connect intravenous infusion catheter/tether system in rats

Alexander et al., Society of Toxicology, Covance, 2007.
FastTether rodent infusion systemratreduced dislodgement

Alternative use of the lateral access port and modifications of caging to support large animal tethered infusion systems

Rose et al., AALAS, MPI Research, 2007.
Cath-In-Cath portsinfusion sets6000 CMS pumps

Arrhythmia detection: a quest for signal quality and computerized tools

Authier, Safety Pharmacology Society webinar, LAB Research.
Cath-In-Cath portsinfusion sets

Add your publication to our growing list

We keep this record as complete as we can, and we miss things. Our part numbers usually sit in a methods section, which search engines do not index, so the only reliable way we hear about a study is from the people who ran it.

If you have published work that used an AVABIO port, catheter, tether system or infusion system, send us the citation and we will add it here with a link. Peer-reviewed papers, conference abstracts, posters and theses all count.

Earlier work, 1996 to 2005

Before AVABIO, our Managing Director led Access Technologies from 1996 to 2001, then directed the clinical, preclinical and OEM divisions at Deltec from 2001, continuing through the company’s change of name to Smiths Medical in 2002 and on until 2005. Work from those years, using products from those divisions, is listed separately so the record stays clear about which device was used where.

Prolonged infusion in marmoset monkeys: feasibility of a port-catheter technique

Nowak et al., 2002.
CADD Micropump Model 5900, Pharmacia Deltecport-catheter systemmarmoset

Feasibility of long-term continuous intravenous infusion in unrestrained marmoset monkeys

Society of Toxicology, 42nd Annual Meeting, 2003, also in Weinbauer et al., The marmoset as a primate model in toxicology: the Covance experience.
CADD Micropump Model 5900, Pharmacia Deltecbackpack systemmarmoset

Methods in vascular infusion biotechnology in research with rodents

ILAR Journal 43(3) 175-191, 2002.doi:10.1093/ilar.43.3.175
Names the CADD peristaltic pump, SIMS-Deltecrodent tetherless infusion

The M1 muscarinic agonist CI-1017 facilitates trace eyeblink conditioning in aging rabbits and increases the excitability of CA1 pyramidal neurons

Weiss, Preston, Oh, Schwarz, Welty and Disterhoft, The Journal of Neuroscience 20(2) 783-790, 2000.doi:10.1523/JNEUROSCI.20-02-00783.2000
Our Managing Director is acknowledged by name in the paper for technical support on the vascular access model.
Access Technologies vascular access portGPV-4S-24 and TI200-4Sfemoral, daily access over the studyrabbitNorthwestern and Parke-Davis
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